SCHEMBL8777417

SCHEMBL8777417

CCCCSN(SCCCC)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
EPHX1 P07099 1/20 0.38
CES1 P23141 5/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 1/20 0.34
CES2 O00748 5/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 2/20 0.33
HPGD P15428 1/20 0.33
GMNN O75496 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
CYP2C9 P11712 1/20 0.33
BLM P54132 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.32
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28741427 0.86 NOS3 (0.37) NOS3NOS1NOS2EPHX1ALDH1A1
SCHEMBL28204335 0.81 CES1 (0.38) NOS3NOS1NOS2EPHX1CES1
Carbamic Acid SCHEMBL1300822 0.81 NOS3 (0.38) NOS3NOS1NOS2EPHX1CES1
Carbamic Acid SCHEMBL1300843 0.79 NOS3 (0.36) NOS3NOS1NOS2EPHX1CES1
SCHEMBL8853371 0.79 HSD17B10 (0.39) CES1CES2ALDH1A1TP53GMNN
SCHEMBL10822669 0.77 ALDH1A1 (0.41) NOS3NOS1NOS2CES1CA1
Hydrochloric Acid SCHEMBL10822670 0.77 HSD17B10 (0.38) CES1CES2ALDH1A1TP53GMNN
SCHEMBL3589766 0.77 NOS3 (0.52) NOS3NOS1NOS2EPHX1ALDH1A1
Zinc Ion SCHEMBL10586397 0.76 CA1 (0.38) CES1CA1CA2CES2ALDH1A1
SCHEMBL4557462 0.75 TSHR (0.32) NOS3NOS1NOS2ALDH1A1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0083075-B1 COLOUR DEVELOPING SHEET FOR A PRESSURE-SENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1986-08-13 EP claimed
US-11950593-B2 Antimicrobial thiouronium copolymers and methods of making and using the same FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INCORPORATED (US) 2024-04-09 US disclosed
US-20220110320-A1 ANTIMICROBIAL THIOURONIUM COPOLYMERS AND METHODS OF MAKING AND USING THE SAME FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INCORPORATED 2022-04-14 US disclosed
EP-0513493-B1 Photosensitive resin composition NIPPON PAINT CO LTD (JP) 1997-12-17 EP disclosed
US-5344744-A For flexographic printing plate, water developable, elasticity wear resistance NIPPON PAINT CO., LTD. (JP) 1994-09-06 US disclosed
EP-0513493-A1 Photosensitive resin composition Nippon Paint Co., Ltd. (JP) 1992-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11950593-B2 Antimicrobial thiouronium copolymers and methods of making and using the same TST, QARS1, TET1 NOS3 1385/4885NOS1 1364/4885NOS2 1231/4885
US-20220110320-A1 ANTIMICROBIAL THIOURONIUM COPOLYMERS AND METHODS OF MAKING AND USING THE SAME TST, QARS1, TET1 NOS3 1385/4885NOS1 1364/4885NOS2 1231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.