SCHEMBL8777482 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MMP3	P08254	17/20	0.44

▸	MMP1	P03956	15/20	0.44

▸	MMP2	P08253	11/20	0.44

▸	MMP9	P14780	8/20	0.44

▸	MMP8	P22894	1/20	0.44

▸	MMP13	P45452	1/20	0.44

▸	MMP14	P50281	1/20	0.44

▸	ADAM17	P78536	1/20	0.44

▸	MMP7	P09237	4/20	0.38

▸	PDF	Q9HBH1	3/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8777469	0.84	MMP1 (0.49)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL8777489	0.77	MMP2 (0.46)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL7372625	0.77	MMP2 (0.51)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL7410230	0.76	MMP3 (0.44)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL8197037	0.76	MMP3 (0.47)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL7596890	0.76	MMP1 (0.52)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL8189622	0.76	MMP3 (0.47)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL7406850	0.76	MMP2 (0.50)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL7368610	0.74	ANPEP (0.43)	MMP3MMP1MMP2MMP9MMP8
SCHEMBL7600843	0.74	MMP1 (0.48)	MMP3MMP1MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0812312-A1	SYNTHESIS OF CARBOXYLIC AND HYDROXAMIC ACID DERIVATIVES	BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB)	1997-12-17	—	—	EP	disclosed
WO-1996026918-A1	SYNTHESIS OF CARBOXYLIC AND HYDROXAMIC ACID DERIVATIVES	BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB)	1996-09-06	—	—	WO	disclosed