SCHEMBL877752

SCHEMBL877752

COS(=O)(=O)c1cccc(N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.61
CA2 P00918 4/20 0.59
CA12 O43570 3/20 0.59
CA1 P00915 3/20 0.59
CA9 Q16790 3/20 0.59
CA4 P22748 2/20 0.59
CA14 Q9ULX7 1/20 0.59
ALDH1A1 P00352 2/20 0.57
TSHR P16473 1/20 0.57
HSD17B10 Q99714 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
F2 P00734 3/20 0.54
PRSS1 P07477 3/20 0.54
PRSS2 P07478 3/20 0.54
PRSS3 P35030 3/20 0.54
CYP3A4 P08684 2/20 0.50
POLB P06746 1/20 0.47
CYP19A1 P11511 1/20 0.45
PKM P14618 3/20 0.44
HTR6 P50406 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28144847 0.86 ALDH1A1 (0.47) LMNACA2CA12CA1CA9
SCHEMBL779123 0.85 CA1 (0.48) LMNACA2CA12CA1CA9
SCHEMBL28794260 0.85 LMNA (0.57) LMNACA2CA12CA1CA9
SCHEMBL28239919 0.83 LMNA (0.65) LMNACA2CA12CA1CA9
SCHEMBL28247680 0.82 LMNA (0.63) LMNACA2CA12CA1CA9
SCHEMBL11529174 0.81 LMNA (0.57) LMNACA2CA12CA1CA9
SCHEMBL2235381 0.80 TDP1 (0.54) LMNACA2CA12CA1CA9
SCHEMBL2296088 0.80 LMNA (0.61) LMNACA2CA12CA1CA9
SCHEMBL28120549 0.80 LMNA (0.61) LMNACA2CA12CA1CA9
SCHEMBL13290766 0.80 NFE2L2 (0.53) CA2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103182165-B Golf DUNLOP SPORTS CO., LTD. (JP) 2015-10-28 CN disclosed
CN-102989132-B Golf ball DUNLOP SPORTS CO LTD 2015-06-10 CN disclosed
EP-2619185-A1 MATRIX METALLOPROTEINASE INHIBITORS Ranbaxy Laboratories Limited (IN) 2013-07-31 EP disclosed
CN-103182165-A Golf ball DUNLOP SPORTS CO LTD 2013-07-03 CN disclosed
WO-2012038942-A1 MATRIX METALLOPROTEINASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2012-03-29 WO disclosed
US-4163059-A Pesticidally active 4,5-dichloro-3-substituted-phenylimino-1,2-dithiolenes BAYER AKTIENGESELLSCHAFT (DE) 1979-07-31 US disclosed