SCHEMBL8777546

SCHEMBL8777546

CCCc1cc(N(C)C)ccc1C(OC)c1ccc(N(C)C)cc1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.37
CALM1 P0DP23 2/20 0.35
GAA P10253 4/20 0.35
ALDH1A1 P00352 4/20 0.33
MAPK1 P28482 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
MEN1 O00255 7/20 0.33
KMT2A Q03164 7/20 0.33
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777747 0.90 GAA (0.35) SLC2A1CALM1GAAALDH1A1MAPK1
SCHEMBL8777538 0.79 GAA (0.34) SLC2A1CALM1GAAALDH1A1MAPK1
SCHEMBL8777640 0.77 SLC2A1 (0.42) SLC2A1CALM1GAAALDH1A1MAPK1
SCHEMBL8777534 0.74 SLC2A1 (0.55) SLC2A1GAAALDH1A1MAPK1TDP1
SCHEMBL8777614 0.73 S100B (0.43) SLC2A1GAAALDH1A1MAPK1TDP1
SCHEMBL8777704 0.72 ALDH1A1 (0.46) SLC2A1CALM1GAAALDH1A1MAPK1
SCHEMBL8777739 0.72 GAA (0.36) SLC2A1GAAALDH1A1MAPK1TDP1
SCHEMBL8777842 0.71 ALDH1A1 (0.39) SLC2A1CALM1GAAALDH1A1MAPK1
SCHEMBL8777735 0.71 SLC16A3 (0.41) SLC2A1GAAALDH1A1MAPK1TDP1
SCHEMBL8777680 0.71 GAA (0.36) SLC2A1GAAMAPK1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed