SCHEMBL8777819

SCHEMBL8777819

CCOc1cc(N(CC)CC)ccc1C(COCC(c1ccc(N(CC)CC)cc1)c1ccc(N(CC)CC)cc1OCC)c1ccc(N(CC)CC)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
RXRA P19793 3/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
TSHR P16473 2/20 0.36
CNR2 P34972 5/20 0.35
MAPK1 P28482 2/20 0.34
PSMD14 O00487 1/20 0.34
CYP3A4 P08684 1/20 0.34
RECQL P46063 1/20 0.34
GFER P55789 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TERT O14746 1/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
RARB P10826 1/20 0.34
RARG P13631 1/20 0.34
PPARG P37231 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777832 0.93 TDP1 (0.39) ALDH1A1L3MBTL1RXRARXRBRXRG
SCHEMBL8777544 0.92 CNR2 (0.36) ALDH1A1L3MBTL1RXRARXRBRXRG
SCHEMBL8777590 0.91 ALDH1A1 (0.41) ALDH1A1L3MBTL1RXRARXRBRXRG
SCHEMBL8777695 0.83 TDP1 (0.45) ALDH1A1L3MBTL1MAPK1GFERTDP1
SCHEMBL5010120 0.82 GRK6 (0.41) ALDH1A1L3MBTL1RXRARXRBRXRG
SCHEMBL8777692 0.81 MEN1 (0.35) ALDH1A1RXRACNR2MAPK1CYP3A4
SCHEMBL8777720 0.81 RXRA (0.42) ALDH1A1L3MBTL1RXRARXRBRXRG
SCHEMBL8777564 0.80 SLC16A3 (0.36) RXRACNR2MAPK1TDP1MAPT
SCHEMBL8777665 0.80 ALDH1A1 (0.39) ALDH1A1L3MBTL1RXRARXRBRXRG
SCHEMBL8777827 0.79 ALDH1A1 (0.41) ALDH1A1L3MBTL1RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed