SCHEMBL8777720

SCHEMBL8777720

CCN(CC)c1ccc(C(COCC(c2ccc(N(C)C)cc2)c2ccc(N(CC)CC)cc2OC(C)C)c2ccc(N(C)C)cc2)c(OC(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.42
RXRB P28702 2/20 0.42
RXRG P48443 2/20 0.42
MEN1 O00255 7/20 0.39
KMT2A Q03164 7/20 0.39
BACE1 P56817 1/20 0.38
TDP1 Q9NUW8 3/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.34
ALDH1A1 P00352 3/20 0.34
NPSR1 Q6W5P4 4/20 0.34
MAPT P10636 3/20 0.34
HTT P42858 3/20 0.34
USP2 O75604 2/20 0.34
GPR35 Q9HC97 2/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
GAA P10253 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777832 0.88 TDP1 (0.39) RXRARXRBRXRGMEN1KMT2A
SCHEMBL8777695 0.88 TDP1 (0.45) MEN1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL8777606 0.82 S100B (0.42) MEN1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL8777725 0.81 RXRA (0.40) RXRARXRBRXRGMEN1KMT2A
SCHEMBL8777819 0.81 ALDH1A1 (0.38) RXRARXRBRXRGMEN1KMT2A
SCHEMBL8777730 0.76 TDP1 (0.42) MEN1KMT2ATDP1MAPK1NPSR1
SCHEMBL8777692 0.76 MEN1 (0.35) RXRAMEN1KMT2ATDP1MAPK1
SCHEMBL8777564 0.75 SLC16A3 (0.36) RXRAMEN1KMT2ATDP1MAPK1
SCHEMBL8777590 0.74 ALDH1A1 (0.41) RXRARXRBRXRGMEN1KMT2A
SCHEMBL9352078 0.74 TDP1 (0.38) RXRAMEN1KMT2ATDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed