Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8688078 | 0.98 | CHRNA7 (0.70) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL873067 | 0.85 | CHRNA7 (0.79) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3217359 | 0.84 | CHRNA7 (1.00) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL8686664 | 0.83 | CHRNA7 (0.77) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9677934 | 0.79 | CHRNA7 (0.64) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4689211 | 0.75 | CHRNA7 (0.64) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9494661 | 0.75 | CHRNA7 (0.58) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9496249 | 0.75 | CHRNA7 (0.58) | CHRNA7 | |
| Oxalic Acid SCHEMBL9492723 | 0.72 | CHRNA7 (0.54) | CHRNA7 | |
| Oxalic Acid SCHEMBL9494045 | 0.72 | CHRNA7 (0.54) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569564-B1 | BIPHENYLYLQUINUCLIDINES, USEFUL AS SQUALENE SYNTHETASE INHIBITORS | ZENECA LTD (GB) | 1997-12-29 | — | — | EP | claimed |
| EP-0569564-A1 | BIPHENYLYLQUINUCLIDINES, USEFUL AS SQUALENE SYNTHETASE INHIBITORS | ZENECA LIMITED (GB) | 1993-11-18 | — | — | EP | claimed |
| WO-1993009115-A1 | BIPHENYLYLQUINUCLIDINES, USEFUL AS SQUALENE SYNTHETASE INHIBITORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-13 | — | — | WO | claimed |