Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | FADS1 | O60427 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17744848 | 0.87 | PTGS1 (0.75) | PTGS1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5666088 | 0.84 | MEN1 (0.69) | PTGS1ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2680413 | 0.83 | LMNA (0.69) | ALDH1A1MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL1961876 | 0.82 | NPC1 (0.68) | PTGS1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL15361168 | 0.82 | SMN1; SMN2 (0.68) | PTGS1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2127535 | 0.82 | PTGS1 (0.69) | PTGS1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL30830441 | 0.82 | PTGS1 (0.69) | PTGS1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1140055 | 0.81 | PTGS1 (0.68) | PTGS1ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL29168835 | 0.81 | KMT2A (0.68) | ALDH1A1MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL1499506 | 0.81 | NPC1 (0.69) | ALDH1A1MAPTNPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160251537-A1 | POLYMER AND COMPOSITIONS THEREOF | LUBRIZOL ADVANCED MATERIALS, INC. | 2016-09-01 | — | — | US | disclosed |
| US-20160251537-A1 | POLYMER AND COMPOSITIONS THEREOF | LUBRIZOL ADVANCED MATERIALS, INC. | 2016-09-01 | — | — | US | disclosed |
| EP-2686356-B1 | POLYMER AND COMPOSITIONS THEREOF | LUBRIZOL ADVANCED MAT INC (US) | 2016-06-15 | — | — | EP | disclosed |
| US-20140024749-A1 | Polymer and Compositions Thereof | LUBRIZOL ADVANCED MATERIALS, INC (US) | 2014-01-23 | — | — | US | disclosed |
| US-20140024749-A1 | Polymer and Compositions Thereof | LUBRIZOL ADVANCED MATERIALS, INC (US) | 2014-01-23 | — | — | US | disclosed |
| US-8546397-B2 | DNA methylation inhibitors | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2012125609-A1 | POLYMER AND COMPOSITIONS THEREOF | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2012-09-20 | — | — | WO | disclosed |
| EP-0665216-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5576335-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0665216-A1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |