Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250338 | 0.98 | SIGMAR1 (0.44) | SIGMAR1CYP19A1SLC18A3OPRM1OPRD1 | |
| SCHEMBL11048072 | 0.98 | SIGMAR1 (0.44) | SIGMAR1CYP19A1SLC18A3OPRM1OPRD1 | |
| SCHEMBL9432698 | 0.95 | SLC18A3 (0.46) | SIGMAR1CYP19A1SLC18A3OPRM1OPRD1 | |
| SCHEMBL9433185 | 0.90 | CYP19A1 (0.44) | SIGMAR1CYP19A1SLC18A3CCR3MEN1 | |
| SCHEMBL11042566 | 0.89 | CTSS (0.47) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11300310 | 0.81 | SIGMAR1 (0.58) | SIGMAR1SLC18A3OPRM1OPRD1OPRK1 | |
| SCHEMBL7286855 | 0.80 | CYP19A1 (0.46) | SIGMAR1CYP19A1SLC18A3CCR3MEN1 | |
| SCHEMBL6049169 | 0.80 | SIGMAR1 (0.61) | SIGMAR1SLC18A3OPRM1OPRD1OPRK1 | |
| SCHEMBL18435050 | 0.80 | SIGMAR1 (0.61) | SIGMAR1CYP19A1SLC18A3OPRM1OPRD1 | |
| SCHEMBL8111557 | 0.79 | CYP19A1 (0.47) | SIGMAR1CYP19A1SLC18A3CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665216-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-12-29 | — | — | EP | disclosed |