SCHEMBL8777968

SCHEMBL8777968

Nc1c(Br)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.67
MAOB P27338 1/20 0.67
ALDH1A1 P00352 9/20 0.62
MEN1 O00255 8/20 0.62
KMT2A Q03164 8/20 0.62
MAPT P10636 6/20 0.62
POLB P06746 6/20 0.62
MAPK1 P28482 5/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
L3MBTL1 Q9Y468 3/20 0.62
LMNA P02545 3/20 0.62
CYP3A4 P08684 3/20 0.62
THRB P10828 2/20 0.62
MCL1 Q07820 2/20 0.62
TSHR P16473 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
CASP3 P42574 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28164454 0.84 S100A4 (0.57) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL357951 0.80 MAPT (0.53) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL487001 0.80 MAOA (1.00) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL30129869 0.80 MAOA (1.00) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL11356479 0.79 MAOA (0.55) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL28010046 0.79 ALDH1A1 (0.59) MAOAMAOBALDH1A1MEN1KMT2A
Bromide SCHEMBL27602610 0.78 MAOA (0.96) MAOAMAOBALDH1A1MEN1KMT2A
Ammonia Solution, Strong SCHEMBL6046897 0.78 MAOA (0.96) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL11314322 0.78 MAOA (0.53) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL28010045 0.77 ALDH1A1 (0.58) MAOAMAOBALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116440837-A Preparation and purification device for 1-amino-2-bromoanthraquinone 浙江德欧化工制造有限公司 2023-07-18 CN claimed
CN-114409555-A Utilization method of bromamine acid by-product 江苏亚邦染料股份有限公司 2022-04-29 CN claimed
CN-104725250-A Preparation method of diamino-anthraquinone HAIMEN JINQILIN REDWOOD INVEST DEV CO LTD 2015-06-24 CN claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
JP-55129249-A None JP disclosed
CN-114456616-B Synthesis method of disperse red 60 常州大学 2024-03-15 CN disclosed
CN-116440837-A Preparation and purification device for 1-amino-2-bromoanthraquinone 浙江德欧化工制造有限公司 2023-07-18 CN disclosed
CN-116440837-A Preparation and purification device for 1-amino-2-bromoanthraquinone 浙江德欧化工制造有限公司 2023-07-18 CN disclosed
CN-116440837-A Preparation and purification device for 1-amino-2-bromoanthraquinone 浙江德欧化工制造有限公司 2023-07-18 CN disclosed
CN-218424055-U Reduce environmental pollution's bromine propylhomoserin and use refining jar 济宁市圣奥精细化工有限公司 2023-02-03 CN disclosed
CN-114456616-A Synthesis method of disperse red 60 常州大学 2022-05-10 CN disclosed
CN-114409555-A Utilization method of bromamine acid by-product 江苏亚邦染料股份有限公司 2022-04-29 CN disclosed
US-4154577-A Uniformly disperse dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4150943-A Uniformly dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed
US-4146535-A Azo dyes having a 3-cyano- or 3-carbamoyl-2,6-diamino-pyridine coupling component BASF AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
US-4105655-A PHENYL-AZO-ANILINO DYESTUFF BAYER AKTIENGESELLSCHAFT (DE) 1978-08-08 US disclosed
US-4083684-A AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4083844-A Phenylazo orthocyano phenylazo or orthocyano phenylazo phenylazo containing dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3962209-A PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed