Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877739 | 0.92 | KDM4A (0.31) | KDM4AKDM4CPOLB | |
| SCHEMBL878098 | 0.86 | HRH4 (0.32) | KDM4AKDM4CPOLB | |
| SCHEMBL877632 | 0.86 | HRH4 (0.31) | KDM4AKDM4CPOLB | |
| SCHEMBL877667 | 0.85 | ACACB (0.32) | KDM4AKDM4CPOLBPDK2 | |
| SCHEMBL878581 | 0.85 | TLR9 (0.33) | PDK2TLR9TLR8TLR7 | |
| SCHEMBL877422 | 0.81 | F10 (0.34) | F10POLB | |
| SCHEMBL876177 | 0.79 | F10 (0.33) | F10F2 | |
| SCHEMBL876281 | 0.78 | F10 (0.37) | F10F2PLATKLKB1KDM4A | |
| SCHEMBL877844 | 0.76 | F10 (0.37) | F10F2PLATKLKB1KDM4A | |
| SCHEMBL785422 | 0.74 | F10 (0.40) | F10F2PLATKLKB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | claimed |