Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479802 | 0.88 | CHRM5 (0.41) | HDAC1HDAC2MRGPRX4CHRM5 | |
| SCHEMBL24305889 | 0.84 | TSHR (0.59) | TSHR | |
| SCHEMBL8955822 | 0.84 | PDK2 (0.49) | HDAC1HDAC2PRSS1 | |
| SCHEMBL14121551 | 0.84 | KIF11 (0.46) | HDAC1HDAC2PRSS1TSHR | |
| SCHEMBL8778594 | 0.83 | TSHR (0.42) | HDAC1HDAC2TSHRMRGPRX4CHRM5 | |
| SCHEMBL1046561 | 0.83 | EPHX2 (0.46) | HDAC1HDAC2MRGPRX4 | |
| SCHEMBL8778595 | 0.83 | EPHX2 (0.46) | HDAC1HDAC2MRGPRX4 | |
| SCHEMBL8778597 | 0.83 | EPHX2 (0.46) | HDAC1HDAC2MRGPRX4 | |
| SCHEMBL8370558 | 0.82 | PIM1 (0.48) | HDAC1HDAC2PRSS1 | |
| SCHEMBL1044641 | 0.81 | EPHX2 (0.47) | HDAC1HDAC2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |