Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370558 | 0.98 | PIM1 (0.48) | PDK2HDAC1HDAC2PIM1PRSS1 | |
| SCHEMBL31466611 | 0.93 | PIM1 (0.52) | PDK2HDAC1HDAC2PIM1FFAR1 | |
| SCHEMBL2095220 | 0.93 | PIM1 (0.52) | PDK2HDAC1HDAC2PIM1FFAR1 | |
| SCHEMBL2097585 | 0.88 | ALDH1A1 (0.52) | PDK2HDAC1HDAC2PIM1FFAR1 | |
| SCHEMBL8955633 | 0.88 | HDAC1 (0.47) | PDK2HDAC1HDAC2PIM1 | |
| SCHEMBL8928364 | 0.86 | PRSS1 (0.55) | PDK2PRSS1 | |
| SCHEMBL8928374 | 0.84 | PRSS1 (0.53) | PDK2PRSS1 | |
| SCHEMBL24305889 | 0.84 | TSHR (0.59) | PDK2 | |
| SCHEMBL14121551 | 0.84 | KIF11 (0.46) | HDAC1HDAC2PRSS1 | |
| SCHEMBL8778525 | 0.84 | HDAC1 (0.45) | HDAC1HDAC2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |