SCHEMBL8778564

SCHEMBL8778564

N#Cc1ccc2c(c1C#N)[C]c1ccccc1-2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.33
USP8 P40818 1/20 0.33
USP7 Q93009 1/20 0.33
ESR2 Q92731 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3923316 0.67 PNMT (0.42) AR
SCHEMBL3230880 0.66
SCHEMBL152358 0.65 TSHR (0.39) ARTSHR
SCHEMBL102781 0.65 MEN1 (0.37) TSHR
SCHEMBL31399295 0.65 TSHR (0.39) ARTSHR
SCHEMBL11876482 0.64 ALDH1A1 (0.46) ESR2
SCHEMBL8726525 0.64 USP8 (0.38) ARUSP8USP7ESR2TSHR
SCHEMBL11132592 0.64 ESR2 (0.43) USP8USP7ESR2TSHR
SCHEMBL11876478 0.63 ESR2 (0.48) USP8USP7ESR2TSHR
SCHEMBL16422435 0.63 AR (0.33) ARUSP8USP7ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8926821-B2 Use of diazonium salts for the formation of thick layers on at least one surface of a substrate COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-01-06 US disclosed
US-20130239661-A1 USE OF DIAZONIUM SALTS FOR THE FORMATION OF THICK LAYERS ON AT LEAST ONE SURFACE OF A SUBSTRATE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2013-09-19 US disclosed
EP-0538112-B1 Electrophotographic photosensitive member, electrophotographic apparatus, device unit and facsimile machine CANON KK (JP) 1997-12-29 EP disclosed
US-5356746-A Containing triazine compound CANON KABUSHIKI KAISHA (JP) 1994-10-18 US disclosed
EP-0538112-A1 Electrophotographic photosensitive member, electrophotographic apparatus, device unit and facsimile machine CANON KABUSHIKI KAISHA (JP) 1993-04-21 EP disclosed
US-4942106-A PHOTOSTABILITY CANON KABUSHIKI KAISHA (JP) 1990-07-17 US disclosed