SCHEMBL8778566

SCHEMBL8778566

[CH2]CCCCCCOc1ccc2ccccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.61
KDM4E B2RXH2 2/20 0.61
MAPK1 P28482 1/20 0.61
HRH3 Q9Y5N1 7/20 0.56
HDAC1 Q13547 2/20 0.56
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
AGXT P21549 2/20 0.53
MAPT P10636 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HTT P42858 1/20 0.51
DRD3 P35462 1/20 0.50
ALOX5 P09917 1/20 0.50
PPARG P37231 2/20 0.49
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16893725 1.00 TDP1 (0.61) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL1534971 1.00 TDP1 (0.61) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL1534924 1.00 TDP1 (0.61) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL16893744 1.00 TDP1 (0.61) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL95651 0.98 TDP1 (0.63) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL7633032 0.92 TDP1 (0.66) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL16902859 0.90 TDP1 (0.73) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL16902857 0.90 TDP1 (0.73) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL16902871 0.90 TDP1 (0.73) TDP1KDM4EMAPK1HRH3HDAC1
SCHEMBL16902870 0.90 TDP1 (0.73) TDP1KDM4EMAPK1HRH3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11952450-B2 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) 2024-04-09 US claimed
US-20220259352-A1 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) 2022-08-18 US claimed
EP-0574355-B1 Phosphinyloxy propanaminium inner salt derivatives CIBA GEIGY AG (CH) 1997-08-13 EP claimed
EP-0656008-A1 THROMBIN RECEPTOR ANTAGONISTS COR THERAPEUTICS, INC. (US) 1995-06-07 EP claimed
EP-0574355-A1 Phosphinyloxy propanaminium inner salt derivatives SANDOZ LTD. (CH) 1993-12-15 EP claimed
US-11952450-B2 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) 2024-04-09 US disclosed
US-20220259352-A1 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) 2022-08-18 US disclosed
CN-112898330-A Compound for packaging organic light-emitting device and preparation method and application thereof 吉林奥来德光电材料股份有限公司 2021-06-04 CN disclosed
US-20150198740-A1 ORGANIC-INORGANIC HYBRID COMPOSITION, PRODUCTION METHOD FOR SAME, AND OPTICAL SHEET AND OPTICAL DEVICE OF SAME CHANGKANG CHEMICAL CO., LTD. (KR) 2015-07-16 US disclosed
EP-0656008-A1 THROMBIN RECEPTOR ANTAGONISTS COR THERAPEUTICS, INC. (US) 1995-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259352-A1 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method AOX1, LOXL1, SEM1 TDP1 2633/4885KDM4E 1440/4885MAPK1 3159/4885
US-11952450-B2 Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method TTPA, LOX, AOX1 TDP1 3350/4885KDM4E 1222/4885MAPK1 4563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.