Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.42 |
| ▸ | DPP4 | P27487 | 5/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838292 | 1.00 | SLC15A1 (0.50) | SLC15A1DPP7LMNASLC1A2SLC1A1 | |
| SCHEMBL8413576 | 0.92 | LMNA (0.52) | SLC15A1DPP7LMNASLC1A2SLC1A1 | |
| SCHEMBL15075211 | 0.88 | SLC1A2 (0.39) | SLC15A1DPP7LMNASLC1A2SLC1A1 | |
| SCHEMBL10205198 | 0.88 | SLC1A2 (0.39) | SLC15A1DPP7LMNASLC1A2SLC1A1 | |
| SCHEMBL28346998 | 0.86 | SLC15A1 (0.49) | SLC15A1DPP7SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL31015685 | 0.86 | FAAH (0.51) | SLC15A1DPP7SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL8778638 | 0.84 | GSR (0.45) | SLC15A1DPP7LMNADPP8DPP4 | |
| SCHEMBL28024261 | 0.84 | TSHR (0.34) | SLC15A1DPP7LMNASLC1A2SLC1A1 | |
| SCHEMBL8778639 | 0.84 | GSR (0.45) | SLC15A1DPP7LMNADPP8DPP4 | |
| SCHEMBL6437091 | 0.82 | GSR (0.53) | DPP7DPP8DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957205-B2 | Cycloalkane carboxamide derivatives and production process of same | SEIKAGAKU CORPORATION (JP) | 2015-02-17 | — | — | US | disclosed |
| US-8829209-B2 | Cycloalkylcarbonylamino acid ester derivative and process for producing the same | SEIKAGAKU CORPORATION (JP) | 2014-09-09 | — | — | US | disclosed |
| EP-2036920-B1 | CYCLOALKYLCARBONYLAMINO ACID ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SEIKAGAKU KOGYO CO LTD (JP) | 2011-05-18 | — | — | EP | disclosed |
| US-20090156805-A1 | Cycloalkane Carboxamide Derivatives and Production Process of Same | SEIKAGAKU CORPORATION (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090137799-A1 | Cycloalkylcarbonylamino Acid Ester Derivative and Process for Producing The Same | SEIKAGAKU CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2036920-A1 | CYCLOALKYLCARBONYLAMINO ACID ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | SEIKAGAKU CORPORATION (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1972615-A1 | CYCLOALKANECARBOXAMIDE DERIVATIVE AND METHOD FOR PRODUCING SAME | SEIKAGAKU CORPORATION (JP) | 2008-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156805-A1 | Cycloalkane Carboxamide Derivatives and Production Process of Same | CTSK, CTSS, CTSB | SLC15A1 2076/4885DPP7 277/4885LMNA 3170/4885 |
| US-20090137799-A1 | Cycloalkylcarbonylamino Acid Ester Derivative and Process for Producing The Same | CTSK, CTSS, CTSE | SLC15A1 1651/4885DPP7 249/4885LMNA 2238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.