SCHEMBL8778760

SCHEMBL8778760

CCC(O)S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.46
ALDH1A1 P00352 6/20 0.46
CA2 P00918 5/20 0.44
CA1 P00915 4/20 0.44
MMP2 P08253 2/20 0.44
MMP1 P03956 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP13 P45452 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
CA12 O43570 4/20 0.43
CA9 Q16790 4/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4725679 0.85 CA2 (0.51) GAAALDH1A1CA2CA1MMP2
SCHEMBL28292240 0.84 GAA (0.46) GAAALDH1A1CA2CA1MMP2
SCHEMBL6396982 0.82 GAA (0.45) GAAALDH1A1CA2CA1MMP2
SCHEMBL2780461 0.82 GAA (0.45) GAAALDH1A1CA2CA1MMP2
SCHEMBL4727639 0.82 CA2 (0.45) GAAALDH1A1CA2CA1MMP2
SCHEMBL8778753 0.82 PSIP1 (0.50) CA2CA1MMP2MMP1MMP9
SCHEMBL7584627 0.81 SMN1; SMN2 (0.44) GAAALDH1A1CA2CA1MMP2
SCHEMBL8473006 0.79 CA2 (0.44) GAAALDH1A1CA2CA1MMP2
SCHEMBL6299378 0.79 GAA (0.42) GAAALDH1A1CA2CA1MMP2
SCHEMBL8971095 0.79 GAA (0.50) GAAALDH1A1CA2CA1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US claimed
EP-0602914-B1 Ink compositions for ink jet printing XEROX CORP (US) 1997-11-12 EP disclosed
EP-0602914-A1 Ink compositions for ink jet printing XEROX CORPORATION (US) 1994-06-22 EP disclosed
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US disclosed