Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 16/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | LDLR | P01130 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785393 | 0.83 | HPGD (0.43) | HPGD | |
| SCHEMBL785456 | 0.83 | HPGD (0.43) | HPGD | |
| SCHEMBL803696 | 0.80 | KMT2A (0.46) | KDM4EHPGD | |
| SCHEMBL803506 | 0.80 | KMT2A (0.46) | KDM4EHPGD | |
| SCHEMBL876311 | 0.76 | ACHE (0.50) | KDM4EHPGDACHE | |
| SCHEMBL877933 | 0.76 | ACHE (0.50) | ACHEMAOAMAOBBCHE | |
| SCHEMBL875980 | 0.71 | ALDH1A1 (0.58) | ACHE | |
| SCHEMBL878469 | 0.71 | ALDH1A1 (0.58) | ACHE | |
| SCHEMBL875578 | 0.71 | ACHE (0.46) | ACHEMAOAMAOBBCHE | |
| SCHEMBL785411 | 0.71 | NAMPT (0.49) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |