Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CIT | O14578 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779278 | 0.91 | HTT (0.39) | HTTGALR3HSP90AA1EPHX2CYP19A1 | |
| SCHEMBL8779223 | 0.88 | AAK1 (0.39) | HTTCIT | |
| SCHEMBL8779253 | 0.84 | HTT (0.39) | HTTGALR3HSP90AA1EPHX2CYP19A1 | |
| SCHEMBL8779210 | 0.84 | CIT (0.30) | CIT | |
| SCHEMBL8779418 | 0.83 | PPARG (0.36) | MCHR1 | |
| SCHEMBL8883147 | 0.82 | HTT (0.39) | HTTGALR3HSP90AA1EPHX2CYP19A1 | |
| SCHEMBL8779325 | 0.81 | IKBKB (0.37) | MAPK1KDM4ECARM1PRMT6 | |
| SCHEMBL8779136 | 0.81 | IKBKB (0.37) | MAPK1KDM4ECARM1PRMT6 | |
| SCHEMBL8779135 | 0.80 | XIAP (0.40) | CARM1PRMT6 | |
| SCHEMBL8779157 | 0.80 | XIAP (0.40) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |