Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 5/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779135 | 1.00 | XIAP (0.40) | XIAPSLC15A1CARM1PRMT6LMNA | |
| SCHEMBL8779165 | 0.97 | XIAP (0.38) | XIAPSLC15A1CARM1PRMT6LMNA | |
| SCHEMBL8779136 | 0.94 | IKBKB (0.37) | XIAPSLC15A1CARM1PRMT6LMNA | |
| SCHEMBL8779325 | 0.94 | IKBKB (0.37) | XIAPSLC15A1CARM1PRMT6LMNA | |
| SCHEMBL8779183 | 0.90 | REN (0.35) | CARM1PRMT6ACACB | |
| SCHEMBL8779140 | 0.90 | REN (0.35) | CARM1PRMT6ACACB | |
| SCHEMBL8779212 | 0.90 | HPGD (0.38) | CARM1PRMT6LMNASMN1; SMN2 | |
| SCHEMBL8779176 | 0.90 | HPGD (0.38) | CARM1PRMT6LMNASMN1; SMN2 | |
| SCHEMBL8779278 | 0.89 | HTT (0.39) | CARM1PRMT6ACACB | |
| SCHEMBL8779292 | 0.86 | CARM1 (0.35) | CARM1PRMT6SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |