Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071615 | 0.72 | GRIN2D (0.44) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11076670 | 0.68 | GRIN2D (0.52) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7401097 | 0.68 | THRB (0.42) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11703847 | 0.68 | — | — | |
| SCHEMBL19472461 | 0.67 | SMN1; SMN2 (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4079487 | 0.67 | GRIN2D (0.45) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| Bicarbonate SCHEMBL20943642 | 0.66 | THRB (0.43) | THRBCYP2C9EPHX1EPHX2HSD11B1 | |
| SCHEMBL6687969 | 0.65 | THRB (0.39) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| Acrylic Acid SCHEMBL3452426 | 0.64 | THRB (0.47) | THRBCYP2C9EPHX1EPHX2DPP4 | |
| Acrylic Acid SCHEMBL2421359 | 0.63 | THRB (0.45) | THRBCYP2C9EPHX1EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | claimed |