SCHEMBL6687969

SCHEMBL6687969

NC(=O)N(C(=O)O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.38
GRIN2D O15399 2/20 0.38
GRIN3B O60391 2/20 0.38
GRIN1 Q05586 2/20 0.38
GRIN2A Q12879 2/20 0.38
GRIN2B Q13224 2/20 0.38
GRIN2C Q14957 2/20 0.38
GRIN3A Q8TCU5 2/20 0.38
EPHX1 P07099 3/20 0.35
NPC1 O15118 1/20 0.35
CRHBP P24387 1/20 0.35
HTT P42858 1/20 0.35
CRHR2 Q13324 1/20 0.35
MCOLN3 Q8TDD5 1/20 0.35
EPHX2 P34913 1/20 0.34
HSD11B1 P28845 1/20 0.34
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6687971 0.89 GRIN2D (0.42) THRBCYP2C9ALDH1A1TSHRGRIN2D
SCHEMBL3071705 0.82 ALDH1A1 (0.37) THRBCYP2C9ALDH1A1TSHRGRIN2D
SCHEMBL22409653 0.76 ALDH1A1 (0.42) THRBCYP2C9ALDH1A1TSHRGRIN2D
SCHEMBL7401097 0.74 THRB (0.42) THRBCYP2C9ALDH1A1TSHRGRIN2D
SCHEMBL6832697 0.73 CYP19A1 (0.33) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL6832695 0.73 EPHX2 (0.52) ALDH1A1EPHX1HTTEPHX2
SCHEMBL3071615 0.73 GRIN2D (0.44) THRBCYP2C9ALDH1A1TSHRGRIN2D
SCHEMBL28751556 0.72 GRIN2D (0.50) THRBCYP2C9ALDH1A1TSHRGRIN2D
SCHEMBL11076670 0.70 GRIN2D (0.52) THRBCYP2C9ALDH1A1TSHRGRIN2D
SCHEMBL6830524 0.68 ALOX5 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed