Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862228 | 0.91 | PTGS1 (0.54) | PTGS1TSHRTTRALDH1A1CFD | |
| SCHEMBL5133639 | 0.85 | PTGS1 (0.68) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL101653 | 0.85 | PTGS1 (0.68) | PTGS1TSHRTTRNR3C1JUN | |
| SCHEMBL9808605 | 0.84 | PTGS1 (0.62) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL7650416 | 0.83 | PTGS1 (0.66) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL20117542 | 0.83 | PTGS1 (0.66) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL357406 | 0.82 | PTGS1 (0.64) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL2357109 | 0.82 | PTGS1 (0.64) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL2729631 | 0.82 | PTGS1 (0.64) | PTGS1TSHRNR3C1JUNNFKB1 | |
| SCHEMBL30074670 | 0.82 | CA2 (0.68) | TTRPOLBALDH1A1LDHACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457192-B | Synthetic method of paradol | 桂林理工大学 | 2023-03-14 | — | — | CN | claimed |
| CN-112457192-A | Synthetic method of paradol | 桂林理工大学 | 2021-03-09 | — | — | CN | claimed |
| CN-112457192-B | Synthetic method of paradol | 桂林理工大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-112457192-B | Synthetic method of paradol | 桂林理工大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-112457192-A | Synthetic method of paradol | 桂林理工大学 | 2021-03-09 | — | — | CN | disclosed |
| CN-112457192-A | Synthetic method of paradol | 桂林理工大学 | 2021-03-09 | — | — | CN | disclosed |
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | disclosed |
| US-5401853-A | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.R.L. (IT) | 1995-03-28 | — | — | US | disclosed |
| EP-0579129-A2 | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) | 1994-01-19 | — | — | EP | disclosed |