Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.66 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | JUN | P05412 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734929 | 0.93 | CYP4F2 (0.66) | PTGS1CYP4F2CYP4A11TSHRNR3C1 | |
| SCHEMBL8010429 | 0.91 | CYP4F2 (0.72) | PTGS1CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL2357109 | 0.87 | PTGS1 (0.64) | PTGS1CYP4F2CYP4A11TSHRNR3C1 | |
| SCHEMBL5133639 | 0.86 | PTGS1 (0.68) | PTGS1CYP4F2CYP4A11TSHRNR3C1 | |
| Acetic Acid SCHEMBL11795359 | 0.86 | LDHA (0.62) | PTGS1CYP4F2CYP4A11ALDH1A1LDHA | |
| Acetic Acid SCHEMBL28278517 | 0.86 | LDHA (0.62) | PTGS1CYP4F2CYP4A11ALDH1A1LDHA | |
| SCHEMBL7650416 | 0.85 | PTGS1 (0.66) | PTGS1CYP4F2CYP4A11TSHRNR3C1 | |
| SCHEMBL20117542 | 0.85 | PTGS1 (0.66) | PTGS1CYP4F2CYP4A11TSHRNR3C1 | |
| SCHEMBL8779397 | 0.85 | PTGS1 (0.66) | PTGS1CYP4F2CYP4A11TSHRNR3C1 | |
| SCHEMBL2729631 | 0.83 | PTGS1 (0.64) | PTGS1TSHRNR3C1JUNNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731991-B2 | Augmenting moieties for anti-inflammatory compounds | LEHIGH UNIVERSITY (US) | 2023-08-22 | — | — | US | claimed |
| US-20200369688-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-11-26 | — | — | US | claimed |
| US-20180305310-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-10-25 | — | — | US | claimed |
| US-20170044096-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | LEHIGH UNIVERSITY | 2017-02-16 | — | — | US | claimed |
| US-9512068-B2 | Augmenting moieties for anti-inflammatory compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-06 | — | — | US | claimed |
| US-20160031804-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | LEHIGH UNIVERSITY | 2016-02-04 | — | — | US | claimed |
| US-11731991-B2 | Augmenting moieties for anti-inflammatory compounds | LEHIGH UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
| US-20200369688-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-11-26 | — | — | US | disclosed |
| US-10752582-B2 | Augmenting moieties for anti-inflammatory compounds | LEHIGH UNIVERSITY (US) | 2020-08-25 | — | — | US | disclosed |
| US-20180305310-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-10-25 | — | — | US | disclosed |
| US-20170044096-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | LEHIGH UNIVERSITY | 2017-02-16 | — | — | US | disclosed |
| US-9512068-B2 | Augmenting moieties for anti-inflammatory compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160031804-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | LEHIGH UNIVERSITY | 2016-02-04 | — | — | US | disclosed |
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | disclosed |
| WO-1996033198-A1 | TUMOR PROTEASE ACTIVATED PRODRUGS OF PHOSPHORAMIDE MUSTARD ANALOGS | DRUG INNOVATION & DESIGN, INC. (US) | 1996-10-24 | — | — | WO | disclosed |
| EP-0533833-B1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1995-12-20 | — | — | EP | disclosed |
| US-5401853-A | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.R.L. (IT) | 1995-03-28 | — | — | US | disclosed |
| EP-0579129-A2 | Thiadiazole derivatives for the treatment of depressive states | LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) | 1994-01-19 | — | — | EP | disclosed |
| EP-0533833-A1 | PHOSPHOROUS PRODRUGS. | GLAZIER ARNOLD (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019721-A1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1991-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731991-B2 | Augmenting moieties for anti-inflammatory compounds | LTC4S, VCAM1, PTGES | PTGS1 12/4885CYP4F2 496/4885CYP4A11 161/4885 |
| US-20180305310-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | PTGES, PTGES3, LRBA | PTGS1 11/4885CYP4F2 875/4885CYP4A11 340/4885 |
| US-10752582-B2 | Augmenting moieties for anti-inflammatory compounds | PTGES, PTGES3, LRBA | PTGS1 11/4885CYP4F2 875/4885CYP4A11 340/4885 |
| US-20160031804-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | PTGES, ICAM1, VCAM1 | PTGS1 9/4885CYP4F2 1504/4885CYP4A11 704/4885 |
| US-20170044096-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | PTGES, PTGES3, LRBA | PTGS1 11/4885CYP4F2 875/4885CYP4A11 340/4885 |
| US-20200369688-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | LTC4S, VCAM1, PTGES | PTGS1 12/4885CYP4F2 496/4885CYP4A11 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.