Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749887 | 1.00 | PMP22 (0.34) | PMP22NOS2GABRR1 | |
| SCHEMBL24180274 | 0.80 | SLC22A6 (0.36) | PMP22GABRR1 | |
| SCHEMBL29493996 | 0.80 | EPHX1 (0.31) | PMP22GABRR1 | |
| SCHEMBL21767029 | 0.78 | KDM4E (0.32) | — | |
| SCHEMBL2437343 | 0.77 | GABRR1 (0.42) | PMP22NOS2GABRR1 | |
| SCHEMBL4898850 | 0.77 | GABRR1 (0.42) | PMP22NOS2GABRR1 | |
| SCHEMBL1601477 | 0.77 | GABRR1 (0.42) | PMP22NOS2GABRR1 | |
| SCHEMBL26788565 | 0.76 | SLC1A3 (0.34) | NOS2 | |
| SCHEMBL8778376 | 0.75 | NOS2 (0.39) | PMP22NOS2 | |
| SCHEMBL24485485 | 0.75 | NOS2 (0.39) | PMP22NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516839-A | Compounds that modulate the CB2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2009-08-26 | — | — | CN | claimed |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-27 | — | — | US | disclosed |
| EP-3331870-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-06-13 | — | — | EP | disclosed |
| US-20170065542-A1 | PHARMACEUTICAL COMPOSITION | OLATEC THERAPEUTICS, INC. | 2017-03-09 | — | — | US | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |
| CN-101516839-A | Compounds that modulate the CB2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2009-08-26 | — | — | CN | disclosed |
| US-7189501-B2 | Silver halide color photographic photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-13 | — | — | US | disclosed |
| CN-1183767-A | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-06-03 | — | — | CN | disclosed |
| EP-0813519-A1 | SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | PMP22 3980/4885NOS2 3588/4885GABRR1 442/4885 |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | PMP22 3980/4885NOS2 3588/4885GABRR1 442/4885 |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | PMP22 3980/4885NOS2 3588/4885GABRR1 442/4885 |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | PMP22 3980/4885NOS2 3588/4885GABRR1 442/4885 |
| US-20170065542-A1 | PHARMACEUTICAL COMPOSITION | FAAH2, CNR2, FFAR3 | PMP22 534/4885NOS2 937/4885GABRR1 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.