Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779478 | 0.88 | ALDH1A1 (0.44) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL11623968 | 0.82 | ALDH1A1 (0.43) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL427816 | 0.78 | RAB9A (0.77) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL127279 | 0.78 | RAB9A (0.77) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL18118972 | 0.78 | RAB9A (0.77) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL29377311 | 0.75 | RAB9A (0.74) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL9515208 | 0.72 | ALDH1A1 (0.58) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL9341571 | 0.72 | RAB9A (0.62) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL23394825 | 0.72 | RAB9A (0.68) | ALDH1A1RAB9AHPGDMAPTMAPK1 | |
| SCHEMBL18934226 | 0.72 | RAB9A (0.68) | ALDH1A1RAB9AHPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621272-B1 | 3,4-Dioxy-1,2,5-thiadiazoles partly useful as fungicides | TOSOH CORP (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5478849-A | Thiadiazole derivative, process for producing it and agricultural and horticultural fungicide using it as an active ingredient | TOSOH CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0621272-A1 | 3,4-Dioxy-1,2,5-thiadiazoles partly useful as fungicides | Tosoh Corporation (JP) | 1994-10-26 | — | — | EP | disclosed |