Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779478 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDRAB9AMAPTNPC1 | |
| SCHEMBL11621874 | 0.83 | MERTK (0.41) | ALDH1A1HPGDRAB9AMAPTNPC1 | |
| SCHEMBL10924387 | 0.83 | MEN1 (0.39) | ALDH1A1HPGDRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8779465 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDRAB9AMAPTNPC1 | |
| SCHEMBL11064204 | 0.80 | NSD2 (0.39) | ALDH1A1HPGDRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL11620743 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11473883 | 0.71 | TOP2A (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL10924379 | 0.71 | P4HB (0.38) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8779443 | 0.69 | ALDH1A1 (0.44) | ALDH1A1HPGDRAB9AMAPTNPC1 | |
| SCHEMBL427816 | 0.67 | RAB9A (0.77) | ALDH1A1HPGDRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097594-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |