SCHEMBL8779544

SCHEMBL8779544

CC1=Cc2ccccc2C1[Zr]C1C(C)=Cc2ccccc21.C[Si](C)(Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL3686216 0.91 LMNA (0.32) LMNA
SCHEMBL28230694 0.91 LMNA (0.33) LMNA
SCHEMBL688487 0.91 LMNA (0.33) LMNA
SCHEMBL29959660 0.91 LMNA (0.33) LMNA
SCHEMBL28294142 0.89 LMNA (0.31) LMNA
SCHEMBL8779601 0.87 LMNA (0.30) LMNA
SCHEMBL8779527 0.87 CYP11B1 (0.30)
SCHEMBL27424309 0.79 LMNA (0.32) LMNA
SCHEMBL5381123 0.78
SCHEMBL8679553 0.77 LMNA (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384180-B2 Polypropylene and method for preparing the same LG CHEM, LTD. 2022-07-12 US disclosed
US-20200140583-A1 Polypropylene And Method For Preparing The Same LG CHEM, LTD. (KR) 2020-05-07 US disclosed
EP-3546489-A1 POLYPROPYLENE AND PREPARATION METHOD THEREFOR LG Chem, Ltd. (KR) 2019-10-02 EP disclosed
EP-0730003-B1 Polypropylene resin composition and molded product TOSOH CORP (JP) 1997-12-29 EP disclosed
US-5608008-A ETHYLENE-A-OLEFIN COPOLYMER ELASTOMER TOSOH CORPORATION (JP) 1997-03-04 US disclosed
EP-0730003-A1 Polypropylene resin composition and molded product Tosoh Corporation (JP) 1996-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384180-B2 Polypropylene and method for preparing the same PPIP5K2, PCBP1, FKBP5 LMNA 1928/4885
US-20200140583-A1 Polypropylene And Method For Preparing The Same PPIP5K2, PCBP1, FKBP5 LMNA 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.