Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687291 | 0.89 | RHEB (0.41) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL8779922 | 0.88 | DAGLA (0.46) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL8779877 | 0.88 | DAGLA (0.46) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL8764783 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL8764792 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL7363077 | 0.70 | ALDH1A1 (0.54) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL10333560 | 0.70 | ALDH1A1 (0.54) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL7275088 | 0.69 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL8765302 | 0.67 | FOLH1 (0.50) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 | |
| SCHEMBL6849355 | 0.67 | FOLH1 (0.50) | ALDH1A1LMNAHSD17B10POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539057-B1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PROD (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0539057-A1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5124319-A | Administering for treatment of neuropathological disorders induced by overstimulation of excitatory amino acid receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |