Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.39 |
| ▸ | PRCP | P42785 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779928 | 0.89 | ALDH1A1 (0.41) | RHEBLMNAALDH1A1POLBHSD17B10 | |
| SCHEMBL8779922 | 0.88 | DAGLA (0.46) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL8779877 | 0.88 | DAGLA (0.46) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL8764792 | 0.74 | ALDH1A1 (0.52) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL8764783 | 0.74 | ALDH1A1 (0.52) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL10333560 | 0.70 | ALDH1A1 (0.54) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL7363077 | 0.70 | ALDH1A1 (0.54) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL7275088 | 0.69 | ALDH1A1 (0.52) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL6849355 | 0.67 | FOLH1 (0.50) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL8765302 | 0.67 | FOLH1 (0.50) | LMNAALDH1A1POLBHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124319-A | Administering for treatment of neuropathological disorders induced by overstimulation of excitatory amino acid receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |