Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692757 | 0.98 | NCF1 (0.38) | KCNA3HTR1BSLC6A4VEGFANCF1 | |
| SCHEMBL8780093 | 0.82 | CNR2 (0.40) | KCNA3HTR1BBCL2BCL2L1MCL1 | |
| SCHEMBL3797699 | 0.82 | CYP1A2 (0.46) | HTR1BSLC6A4HRH1 | |
| SCHEMBL3791996 | 0.80 | CYP2A6 (0.45) | HTR1BMEN1KMT2A | |
| SCHEMBL8780105 | 0.77 | TDP1 (0.63) | MEN1KMT2AHTR2A | |
| SCHEMBL7694129 | 0.77 | NCF1 (0.37) | KCNA3HTR1BSLC6A4NCF1MEN1 | |
| SCHEMBL827357 | 0.76 | ALDH1A1 (0.45) | MEN1KMT2ADRD2 | |
| SCHEMBL8780097 | 0.76 | HRH3 (0.62) | MEN1KMT2AHTR2A | |
| SCHEMBL8780099 | 0.76 | HRH3 (0.62) | MEN1KMT2AHTR2A | |
| SCHEMBL8780109 | 0.75 | HRH3 (0.64) | MEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662964-B1 | HETEROCYCLIC AMINES HAVING CALMODULIN ANTAGONIST PROPERTIES | BRITISH TECH GROUP (GB) | 1997-06-11 | — | — | EP | disclosed |
| US-5543422-A | HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS, FUNGICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-08-06 | — | — | US | disclosed |
| EP-0662964-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES. | BRITISH TECH GROUP (GB) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994007875-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |