Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 15/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472895 | 0.81 | HTT (0.46) | PTPN11 | |
| SCHEMBL717427 | 0.80 | ALDH1A1 (0.59) | TP53TSHR | |
| SCHEMBL9601334 | 0.80 | ALDH1A1 (0.59) | TP53TSHR | |
| SCHEMBL716141 | 0.77 | TSHR (0.57) | TP53TSHR | |
| SCHEMBL30848518 | 0.74 | NR5A1 (0.45) | PLA2G4BTSHRPTPN11 | |
| SCHEMBL3668740 | 0.74 | NR5A1 (0.45) | PLA2G4BTSHRPTPN11 | |
| SCHEMBL9483604 | 0.74 | MCHR1 (0.51) | TSHR | |
| SCHEMBL30132038 | 0.74 | MCHR1 (0.51) | TSHR | |
| SCHEMBL28383663 | 0.74 | MCHR1 (0.51) | TSHR | |
| SCHEMBL30060808 | 0.74 | MCHR1 (0.51) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |