Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550989 | 0.87 | DRD2 (0.56) | DRD2SIGMAR1CHRNA7KCNH2HTR1A | |
| SCHEMBL9825418 | 0.81 | HTR1A (0.50) | DRD2SIGMAR1CHRNA7KCNH2HTR1A | |
| SCHEMBL740054 | 0.80 | CHRNA7 (0.58) | DRD2SIGMAR1CHRNA7KCNH2HTR1A | |
| SCHEMBL8972630 | 0.79 | THRB (0.40) | THRBKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL4175721 | 0.79 | THRB (0.40) | THRBKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL10378875 | 0.79 | THRB (0.40) | THRBKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL14896053 | 0.79 | CHRNA7 (0.49) | DRD2SIGMAR1CHRNA7KCNH2HTR1A | |
| SCHEMBL14479173 | 0.78 | POLB (0.41) | DRD2LMNATSHRKDM4EGAA | |
| Hexadecane SCHEMBL28172309 | 0.76 | DRD2 (0.55) | DRD2SIGMAR1CHRNA7KCNH2NPSR1 | |
| SCHEMBL15920946 | 0.76 | KCNH2 (0.83) | DRD2SIGMAR1CHRNA7KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |