Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.45 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | PRNP | P04156 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119822 | 0.78 | RARB (0.43) | PDE7APDE7B | |
| SCHEMBL8780435 | 0.71 | TSHR (0.45) | PDE7APDE7BLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8780486 | 0.68 | NR1H4 (0.39) | PDE7APDE7BLMNAALDH1A1DHFR | |
| SCHEMBL9121304 | 0.67 | TLR7 (0.43) | PDE7APDE7BKMT2ALMNAMEN1 | |
| SCHEMBL9654563 | 0.66 | PDE7A (0.49) | PDE7APDE7B | |
| SCHEMBL6493237 | 0.64 | PDE10A (0.54) | PDE7APDE7BKMT2ALMNAMEN1 | |
| SCHEMBL6216951 | 0.64 | DHFR (0.49) | PDE7APDE7BKMT2ALMNAMEN1 | |
| SCHEMBL4058443 | 0.63 | ADAM17 (0.54) | PDE7APDE7BKMT2ALMNAMEN1 | |
| SCHEMBL6211757 | 0.63 | MEN1 (0.50) | PDE7APDE7BKMT2ALMNAMEN1 | |
| Benzoic Acid SCHEMBL7064148 | 0.61 | SRD5A2 (0.71) | KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498722-B1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1997-07-30 | — | — | EP | disclosed |
| EP-0498722-A1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |