Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 9/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239976 | 1.00 | PTPN11 (0.60) | PTPN11LMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL11511175 | 0.94 | PTPN11 (0.54) | PTPN11TSHRMEN1KMT2APLK1 | |
| SCHEMBL5149360 | 0.90 | HNF4A (0.50) | PTPN11ALDH1A1KMT2ALTB4R2HNF4A | |
| SCHEMBL21410539 | 0.88 | ALDH1A1 (0.65) | PTPN11LMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL6757271 | 0.87 | PTPN11 (0.57) | PTPN11LMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL32670803 | 0.87 | PTPN11 (0.57) | PTPN11LMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL11340527 | 0.85 | HNF4A (0.54) | LMNAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12765498 | 0.84 | PTPN11 (0.47) | PTPN11LMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL5156328 | 0.84 | HNF4A (0.53) | PTPN11LMNAALDH1A1CYP3A4MEN1 | |
| SCHEMBL12121551 | 0.84 | PTPN11 (0.47) | PTPN11LMNATSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |