Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342291 | 0.81 | POLB (0.45) | POLBESR1ALDH1A1TP53CYP3A4 | |
| SCHEMBL29653561 | 0.81 | POLB (0.45) | POLBESR1ALDH1A1TP53CYP3A4 | |
| SCHEMBL11661680 | 0.76 | HSPA5 (0.42) | POLBESR1ALDH1A1TP53CYP3A4 | |
| SCHEMBL307367 | 0.73 | ALDH1A1 (0.55) | POLBSKP2ESR1ALDH1A1TP53 | |
| SCHEMBL15745652 | 0.72 | AR (0.34) | POLBESR1ALDH1A1SHBGAR | |
| Ammonia Solution, Strong SCHEMBL3031871 | 0.71 | ALDH1A1 (0.52) | POLBSKP2ESR1ALDH1A1TP53 | |
| SCHEMBL15733061 | 0.70 | SMN1; SMN2 (0.45) | POLBESR1ALDH1A1TP53CYP3A4 | |
| SCHEMBL2155153 | 0.69 | POLB (0.41) | POLBSKP2ESR1ALDH1A1TP53 | |
| SCHEMBL10905421 | 0.69 | HSPA5 (0.37) | POLBESR1ALDH1A1TP53CYP3A4 | |
| SCHEMBL8861189 | 0.68 | SHBG (0.41) | SKP2ALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477440-B1 | Self-locking agent | THREE BOND CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5352308-A | Self-locking agent | THREE BOND CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0477440-A1 | Self-locking agent | THREE BOND CO., LTD. (JP) | 1992-04-01 | — | — | EP | disclosed |