Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626008 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTFNTA | |
| SCHEMBL19717960 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTFNTA | |
| SCHEMBL214415 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMAPTFNTA | |
| SCHEMBL10812462 | 0.85 | FNTA (0.56) | ALDH1A1MEN1KMT2AMAPTFNTA | |
| SCHEMBL10812465 | 0.85 | FNTA (0.56) | ALDH1A1MEN1KMT2AMAPTFNTA | |
| SCHEMBL29179222 | 0.78 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AMAPTFNTA | |
| Lyral SCHEMBL5986927 | 0.76 | MEN1 (0.44) | ALDH1A1MEN1KMT2AMAPTFNTA | |
| SCHEMBL10708005 | 0.74 | CES2 (0.33) | ALDH1A1ALOX15CYP1B1 | |
| SCHEMBL11701932 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AMAPTALOX15 | |
| SCHEMBL13976301 | 0.72 | PLA2G2A (0.47) | ALDH1A1MEN1KMT2AMAPTFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797569-A1 | CYCLOHEX(EN)YL-PROPIONITRILES | QUEST INTERNATIONAL (NL) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018604-A1 | CYCLOHEX(EN)YL-PROPIONITRILES | QUEST INTERNATIONAL (NL) | 1996-06-20 | — | — | WO | disclosed |