Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.47 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612426 | 0.95 | ESR1 (0.56) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL8780620 | 0.92 | ESR1 (0.51) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL8780626 | 0.92 | ESR1 (0.46) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL9612352 | 0.92 | ESR1 (0.51) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL10019152 | 0.88 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL16683251 | 0.88 | ESR1 (0.57) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL19871618 | 0.87 | ESR1 (0.53) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL8780510 | 0.86 | ESR1 (0.54) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL2604847 | 0.86 | ESR1 (0.56) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL23759389 | 0.85 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-8986852-B2 | Benzanthracene derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| US-8986852-B2 | Benzanthracene derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| EP-2148909-B1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-30 | — | — | EP | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| WO-2011012212-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-02-03 | — | — | WO | disclosed |
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| WO-2008145239-A2 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | KCNT1, KCNC1, TMEM109 | ESR1 667/4885ESR2 510/4885GRIA1 1047/4885 |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MYB, L1CAM, SLC25A21 | ESR1 703/4885ESR2 698/4885GRIA1 3588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.