Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290471 | 0.82 | SLC1A3 (0.54) | TSHRSLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL722389 | 0.82 | SLC1A3 (0.54) | TSHRSLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL7291825 | 0.82 | SLC1A3 (0.54) | TSHRSLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL27742181 | 0.80 | SLC1A3 (0.52) | TSHRSLC1A3SLC1A2SLC1A1TP53 | |
| Ethylene Glycol SCHEMBL3744577 | 0.74 | SLC1A3 (0.46) | TSHRSLC1A3SLC1A2SLC1A1TP53 | |
| Propylene Glycol SCHEMBL3726880 | 0.71 | SLC1A3 (0.43) | TSHRSLC1A3SLC1A2SLC1A1TP53 | |
| 1,4-Butanediol SCHEMBL3733977 | 0.71 | SLC1A3 (0.43) | TSHRSLC1A3SLC1A2SLC1A1PGD | |
| SCHEMBL915072 | 0.71 | TSHR (0.53) | TSHRSLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL20839610 | 0.69 | TSHR (0.50) | TSHRSLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL1068276 | 0.69 | TSHR (0.50) | TSHRSLC1A3SLC1A2SLC1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658880-A | PREVENT SELECTIN BINDING; ANTIINFLAMMATORY, ANTICANCER AGENTS; AIDS THERAPY | GLYCOMED INCORPORATED (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0775151-A2 | SIALIC ACID/FUCOSE BASED MEDICAMENTS | GLYCOMED INCORPORATED (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005209-A9 | SIALIC ACID/FUCOSE BASED MEDICAMENTS | — | 1996-04-11 | — | — | WO | disclosed |
| WO-1996005209-A2 | SIALIC ACID/FUCOSE BASED MEDICAMENTS | GLYCOMED, INCORPORATED (US) | 1996-02-22 | — | — | WO | disclosed |