Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.39 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.36 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472382 | 0.94 | LPAR1 (0.39) | SLC2A1LPAR1MAPTL3MBTL1KDM4E | |
| SCHEMBL1492154 | 0.94 | LPAR1 (0.39) | SLC2A1LPAR1MAPTL3MBTL1KDM4E | |
| SCHEMBL8463579 | 0.89 | MAPT (0.35) | F10MAPTPDE4AL3MBTL1MEN1 | |
| SCHEMBL6570405 | 0.86 | SLC2A1 (0.39) | SLC2A1SLC2A4SLC2A8F10TUBB4A | |
| SCHEMBL6572477 | 0.86 | SLC2A1 (0.39) | SLC2A1SLC2A4SLC2A8F10TUBB4A | |
| SCHEMBL7181772 | 0.81 | F10 (0.38) | F10TUBB1MAPTL3MBTL1MEN1 | |
| SCHEMBL7176769 | 0.81 | F10 (0.38) | F10TUBB1MAPTL3MBTL1MEN1 | |
| SCHEMBL6572534 | 0.79 | SLC2A4 (0.39) | SLC2A1SLC2A4SLC2A8TUBB4ATUBB | |
| Timcodar SCHEMBL3673444 | 0.79 | L3MBTL1 (0.37) | SLC2A1F10LPAR1L3MBTL1ALDH1A1 | |
| SCHEMBL6570448 | 0.79 | L3MBTL1 (0.37) | SLC2A1F10LPAR1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797567-A1 | NOVEL AMINO ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY | Vertex Pharmaceuticals Incorporated (US) | 1997-10-01 | — | — | EP | claimed |
| WO-1996015101-A1 | NOVEL AMINO ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1996-05-23 | — | — | WO | claimed |