Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GSR | P00390 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780507 | 0.97 | ESR1 (0.42) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL13249119 | 0.91 | GSR (0.44) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL9976959 | 0.87 | ESR1 (0.46) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL8780625 | 0.87 | GSR (0.41) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL22707965 | 0.85 | ESR1 (0.44) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL8780667 | 0.84 | ESR1 (0.53) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL8780660 | 0.83 | ESR1 (0.41) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL8780792 | 0.83 | GSR (0.46) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL9976885 | 0.83 | ESR1 (0.42) | ESR1ESR2ALDH1A1HPGDKDM4E | |
| SCHEMBL9976948 | 0.82 | ESR1 (0.44) | ESR1ESR2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-8986852-B2 | Benzanthracene derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| US-8986852-B2 | Benzanthracene derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| WO-2011012212-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-02-03 | — | — | WO | disclosed |
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | KCNT1, KCNC1, TMEM109 | ESR1 667/4885ESR2 510/4885ALDH1A1 26/4885 |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MYB, L1CAM, SLC25A21 | ESR1 703/4885ESR2 698/4885ALDH1A1 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.