Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780527 | 0.96 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP1A2HPGDL3MBTL1 | |
| SCHEMBL18394742 | 0.94 | L3MBTL1 (0.48) | ALDH1A1HSD17B10CYP1A2HPGDL3MBTL1 | |
| SCHEMBL30005762 | 0.94 | L3MBTL1 (0.48) | ALDH1A1HSD17B10CYP1A2HPGDL3MBTL1 | |
| SCHEMBL8780702 | 0.90 | KDM4E (0.44) | ALDH1A1HSD17B10CYP1A2HPGDL3MBTL1 | |
| SCHEMBL9890871 | 0.90 | L3MBTL1 (0.47) | ALDH1A1HSD17B10HPGDL3MBTL1KDM4E | |
| SCHEMBL18395044 | 0.90 | L3MBTL1 (0.50) | ALDH1A1HSD17B10HPGDL3MBTL1KDM4E | |
| SCHEMBL30005900 | 0.90 | L3MBTL1 (0.50) | ALDH1A1HSD17B10HPGDL3MBTL1KDM4E | |
| SCHEMBL8780718 | 0.89 | L3MBTL1 (0.46) | ALDH1A1HSD17B10CYP1A2HPGDL3MBTL1 | |
| SCHEMBL18548892 | 0.88 | L3MBTL1 (0.46) | ALDH1A1HSD17B10HPGDL3MBTL1KDM4E | |
| SCHEMBL18406155 | 0.88 | L3MBTL1 (0.48) | ALDH1A1HSD17B10HPGDL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| WO-2011012212-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MYB, L1CAM, SLC25A21 | ALDH1A1 507/4885HSD17B10 1679/4885CYP1A2 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.