Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TYMP | P19971 | 4/20 | 0.41 |
| ▸ | TK1 | P04183 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097790 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTALDH1A1CYP2C19 | |
| SCHEMBL10475653 | 0.84 | TYMP (0.37) | TYMPTK1HPGD | |
| SCHEMBL10474801 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2TYMPTK1MAPK1HPGD | |
| SCHEMBL18249895 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2TYMPMAPK1HTTHPGD | |
| SCHEMBL17986375 | 0.76 | TYMP (0.45) | SMN1; SMN2TYMPTK1 | |
| SCHEMBL17758847 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2TYMPTK1MAPK1HPGD | |
| Triphosphate SCHEMBL10475441 | 0.74 | TYMP (0.46) | SMN1; SMN2TYMPTK1ALDH1A1 | |
| SCHEMBL8444516 | 0.74 | TYMP (0.49) | TYMPTK1MAPK1HPGD | |
| SCHEMBL6153438 | 0.74 | MAPK1 (0.42) | SMN1; SMN2TYMPTK1MAPK1HTT | |
| SCHEMBL14425022 | 0.73 | TK1 (0.38) | TYMPTK1MAPK1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766691-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035304-A1 | HYDROXYALKYLAMMONIUM-PYRIMIDINES OR PURINES AND NUCLEOSIDE DERIVATIVES, USEFUL AS INHIBITORS OF INFLAMMATORY CYTOKINES | MACRONEX, INC. (US) | 1995-12-28 | — | — | WO | disclosed |