Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.43 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312814 | 0.85 | SLC6A9 (0.70) | SLC6A9KCNH2OPRL1HTR1AHTR1D | |
| SCHEMBL1387524 | 0.72 | SLC6A9 (0.84) | SLC6A9KCNH2OPRL1HTR1AHTR1D | |
| SCHEMBL8185864 | 0.72 | SLC6A9 (0.83) | SLC6A9KCNH2OPRL1HTR1AHTR1D | |
| SCHEMBL27394523 | 0.71 | HTR1A (0.53) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL7810217 | 0.71 | HTR1A (0.69) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7810671 | 0.71 | SLC6A9 (0.82) | SLC6A9KCNH2OPRL1HTR1AHTR1D | |
| SCHEMBL7813346 | 0.71 | SLC6A9 (0.76) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL6308994 | 0.71 | HTR1A (0.54) | SLC6A9KCNH2HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7813268 | 0.70 | SLC6A9 (0.82) | SLC6A9KCNH2OPRL1HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL7813281 | 0.70 | SLC6A9 (0.96) | SLC6A9KCNH2OPRL1HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020183011-A1 | HTR1D INHIBITORS AND USES THEREOF IN THE TREATMENT OF CANCER | INSTITUT CURIE (FR) | 2020-09-17 | — | — | WO | disclosed |
| EP-0795328-A1 | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1997-09-17 | — | — | EP | disclosed |