Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780741 | 0.85 | SLC6A9 (0.71) | SLC6A9KCNH2OPRL1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1387548 | 0.83 | SLC6A9 (0.69) | SLC6A9KCNH2OPRL1ALDH1A1L3MBTL1 | |
| SCHEMBL1387863 | 0.75 | RAB9A (0.53) | ALDH1A1L3MBTL1NPC1POLBCASP3 | |
| SCHEMBL8187068 | 0.75 | ALOX5AP (0.41) | SLC6A9KCNH2OPRL1ALDH1A1HTR1B | |
| SCHEMBL7803546 | 0.75 | HTR1A (0.42) | SLC6A9KCNH2HTR1BHTR1AHTR1D | |
| SCHEMBL7803556 | 0.72 | SLC6A9 (0.40) | SLC6A9KCNH2HTR1BEPHA2KDR | |
| SCHEMBL27371802 | 0.71 | HTR1A (0.41) | SLC6A5HTR1BHTR1AHTR1D | |
| SCHEMBL7816032 | 0.71 | HTR1A (0.41) | SLC6A9KCNH2L3MBTL1HTR1BHTR1A | |
| SCHEMBL7812267 | 0.71 | SLC6A9 (0.44) | SLC6A9KCNH2OPRL1L3MBTL1NPC1 | |
| SCHEMBL9325324 | 0.71 | MTNR1A (0.56) | HTR1BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H09506638-A | — | — | 1997-06-30 | — | — | JP | claimed |
| EP-0767782-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000720-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-11 | — | — | WO | claimed |
| US-6166020-A | Aryl and heteroaryl alkoxynaphthalene derivatives | PFIZER INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0795328-A1 | Use of naphthalene derivatives in treating lung carcinoma | PFIZER INC. (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0767782-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000720-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-11 | — | — | WO | disclosed |