Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | PARG | Q86W56 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780812 | 0.87 | ALDH1A1 (0.37) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL8603091 | 0.85 | ALDH1A1 (0.35) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL8606043 | 0.81 | NSD2 (0.40) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL8780846 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL6737493 | 0.77 | NSD2 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL8536233 | 0.77 | TBXA2R (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL8780764 | 0.74 | ACLY (0.37) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL8661923 | 0.69 | CDK1 (0.43) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL6738181 | 0.67 | MAPT (0.40) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL28000084 | 0.66 | AOC3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790985-A1 | N-ACYL-N-ALKYLAMINO PHENYL SULPHONYL UREAS WITH SULPHUR SUBSTITUENTS, PROCESS FOR THEIR PRODUCTION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014304-A1 | N-ACYL-N-ALKYLAMINO PHENYL SULPHONYL UREAS WITH SULPHUR SUBSTITUENTS, PROCESS FOR THEIR PRODUCTION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1996-05-17 | — | — | WO | disclosed |