Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.52 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780960 | 0.85 | DRD2 (0.59) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9386254 | 0.84 | KCNH2 (0.66) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL8780808 | 0.83 | TAAR1 (0.45) | SMN1; SMN2CYP3A4TAAR1 | |
| SCHEMBL9383710 | 0.82 | KCNH2 (0.64) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL8780944 | 0.82 | TAAR1 (0.60) | SMN1; SMN2TAAR1 | |
| SCHEMBL8781016 | 0.81 | KCNH2 (0.56) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9384586 | 0.81 | KCNH2 (0.68) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL9387321 | 0.81 | KCNH2 (0.68) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| SCHEMBL8780816 | 0.81 | KCNH2 (0.59) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 | |
| Hydrochloric Acid SCHEMBL9383350 | 0.81 | KCNH2 (0.67) | KCNH2SLC22A2ADRB1SLC6A4SLC47A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |