Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25980025 | 0.74 | KMT2A (0.44) | MAPTALDH1A1NPSR1RXFP1KMT2A | |
| SCHEMBL70626 | 0.74 | CYP4F2 (0.46) | MAPTALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7011885 | 0.73 | MAPT (0.47) | MAPTALDH1A1PKMNPSR1HTT | |
| SCHEMBL23710639 | 0.71 | MAPK1 (0.48) | ALDH1A1NPSR1RXFP1KMT2ASMN1; SMN2 | |
| SCHEMBL20515256 | 0.70 | RXFP1 (0.46) | ALDH1A1NPSR1RXFP1KMT2ASMN1; SMN2 | |
| SCHEMBL25980021 | 0.70 | KMT2A (0.44) | ALDH1A1NPSR1RXFP1KMT2ASMN1; SMN2 | |
| SCHEMBL25980024 | 0.70 | ALDH1A1 (0.44) | ALDH1A1NPSR1RXFP1KMT2ASMN1; SMN2 | |
| SCHEMBL25980052 | 0.69 | MAPT (0.62) | MAPTALDH1A1PKMNPSR1HTT | |
| SCHEMBL9868496 | 0.69 | NPC1 (0.55) | MAPTSMN1; SMN2 | |
| SCHEMBL22862695 | 0.69 | TSHR (0.59) | MAPTALDH1A1HTTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |