Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780936 | 0.83 | KCNH2 (0.54) | GRIN1GRIN2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL8780780 | 0.82 | KCNH2 (0.42) | GRIN1GRIN2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL8780808 | 0.82 | TAAR1 (0.45) | ALDH1A1HPGDSMN1; SMN2TAAR1RXFP1 | |
| SCHEMBL8780747 | 0.81 | KDM4E (0.42) | GRIN1GRIN2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL8780896 | 0.81 | KCNH2 (0.42) | GRIN1GRIN2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL8780944 | 0.81 | TAAR1 (0.60) | ALDH1A1LMNAHPGDSMN1; SMN2TAAR1 | |
| SCHEMBL8780864 | 0.81 | KCNH2 (0.44) | GRIN1GRIN2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL8780929 | 0.81 | KCNH2 (0.42) | GRIN1GRIN2BKCNH2ALDH1A1KDM4E | |
| SCHEMBL8780847 | 0.80 | KCNH2 (0.40) | GRIN1GRIN2BKCNH2ALDH1A1ADRB2 | |
| SCHEMBL8780894 | 0.80 | KCNH2 (0.44) | GRIN1GRIN2BKCNH2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |