SCHEMBL878089

SCHEMBL878089

CCCCCCCCCCCCc1cc2cc(CCCCCCCCCCCC)c1o2

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.43
TYR P14679 2/20 0.43
CYP3A4 P08684 2/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LIPG Q9Y5X9 1/20 0.40
HCAR2 Q8TDS4 2/20 0.40
PTGS2 P35354 6/20 0.39
HTR2A P28223 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25417724 1.00 ALOX5 (0.43) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL25415956 0.98 ALOX5 (0.40) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL28737834 0.94 HCAR2 (0.40) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL7606700 0.91 CTRC (0.40) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL7178215 0.89 ALOX5 (0.39) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL4424837 0.86 CTRC (0.41) TYRMEN1MAPTHTTKMT2A
SCHEMBL29431493 0.86 CTRC (0.41) TYRMEN1MAPTHTTKMT2A
SCHEMBL157308 0.82 ESR1 (0.37) CYP3A4MAPTTSHRHTTHCAR2
SCHEMBL29365621 0.80 MAPT (0.40) TYRMEN1MAPTHTTKMT2A
SCHEMBL788068 0.80 MAPT (0.40) TYRMEN1MAPTHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118185280-A Flame-retardant modified polyphenylene oxide resin composition having excellent deformation resistance and mechanical properties and molded article made of the same 韩华道达尔能源有限公司 2024-06-14 CN claimed
EP-3286022-B1 TYRE READY TO RECEIVE A MEMBER ON THE SURFACE THEREOF MICHELIN & CIE (FR) 2021-06-09 EP claimed
CN-107532052-B Tyre for receiving a component on a surface 米其林集团总公司 2020-05-01 CN claimed
EP-2516549-B1 PNEUMATIC TIRE PROVIDED WITH A GAS-TIGHT LAYER COMPRISING A STYRENE THERMOPLASTIC ELASTOMER AND A POLYPHENYLENE ETHER MICHELIN & CIE (FR) 2018-11-07 EP claimed
US-20180086159-A1 TIRE READY TO RECEIVE A MEMBER ON THE SURFACE THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-03-29 US claimed
EP-3286022-A1 TYRE READY TO RECEIVE A MEMBER ON THE SURFACE THEREOF Compagnie Générale des Etablissements Michelin (FR) 2018-02-28 EP claimed
WO-2017220897-A1 TYRE READY TO RECEIVE A MEMBER ON THE SURFACE THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-12-28 WO claimed
WO-2017220895-A1 TYRE READY TO RECEIVE A MEMBER ON THE SURFACE THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-12-28 WO claimed
WO-2016169764-A1 TYRE READY TO RECEIVE A MEMBER ON THE SURFACE THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-10-27 WO claimed
US-20120285597-A1 PNEUMATIC OBJECT PROVIDED WITH A GAS-TIGHT LAYER COMPRISING A STYRENE THERMOPLASTIC ELASTOMER AND A POLYPHENYLENE ETHER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2012-11-15 US claimed
CN-102686666-A Pneumatic object provided with a gas-tight layer comprising a styrene thermoplastic elastomer and a polyphenylene ether MICHELIN SOC TECH 2012-09-19 CN claimed
WO-2011076802-A1 PNEUMATIC OBJECT PROVIDED WITH A GAS-TIGHT LAYER COMPRISING A STYRENE THERMOPLASTIC ELASTOMER AND A POLYPHENYLENE ETHER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2011-06-30 WO claimed
EP-1865028-B1 Bromine and chlorine-free polycarbonate moulding materials ROMIRA GMBH (DE) 2009-12-30 EP claimed
EP-1636314-A1 MOLDED, FILLED COMPOSITIONS WITH REDUCED SPLAY AND A METHOD OF MAKING General Electric Company (US) 2006-03-22 EP claimed
EP-1612227-A1 Shear degradation inhibitor for triblock thermoplastic elastomers BRIDGESTONE CORPORATION (JP) 2006-01-04 EP claimed
WO-2005003236-A1 MOLDED, FILLED COMPOSITIONS WITH REDUCED SPLAY AND A METHOD OF MAKING GENERAL ELECTRIC COMPANY (US) 2005-01-13 WO claimed
WO-2004052940-A2 SHEAR DEGRADATION INHIBITOR FOR TRIBLOCK THERMOPLASTIC ELASTOMERS BRIDGESTONE CORPORATION (JP) 2004-06-24 WO claimed
US-20040116601-A1 Shear degradation inhibitor for triblock thermoplastic elastomers BFS DIVERSIFIED PRODUCTS, LLC 2004-06-17 US claimed
WO-1992002579-A1 USE OF PHOSPHOROUSTRISLACTAMS AS COMPATIBILIZING AGENTS FOR POLYPHENYLENE OXIDE/POLYESTER BLENDS ALLIED-SIGNAL INC. (US) 1992-02-20 WO claimed
EP-0436136-A1 Compatibilized polyphenylene ehter resin/nylon resin blends containing aromatic phosphorous-containing compounds GENERAL ELECTRIC COMPANY (US) 1991-07-10 EP claimed